Science · listening at the cell surface

From ancient to future receptors.

We combine phylogenomics, synthetic biology, biochemistry, and plant biology to understand how plants perceive the environment.

A luminous bouquet of yellow bell flowers arranged with a miniature car, a Tsurumi train sign, and small animals against a midnight-blue background

How does a plant receptor acquire a new biological function?

Most plant cell-surface receptors share a common origin, yet they have evolved to sense remarkably different signals. We trace how these receptors diversified, discover what they recognize, and uncover the molecular changes that tune their specificity.

Hover, focus or tap a direction to explore.

Evolution gives us the experiment.

The breadth of plant diversity, explored through phylogenomics, helps us decide where to look, what to test, and how to uncover new receptor functions.

1,750+plant species
50+plant orders
60M+proteins
Hundreds of thousandscell-surface receptors
Species in motion · a new selection on every visitGathering 30 species…
Our experimental loop

See. Test. Learn. Build. Repeat.

  1. 01SeePhylogenomics · sequence diversity · co-evolution
  2. 02TestReceptors · ligands · in planta data
  3. 03LearnStructure prediction · protein structure · biochemistry
  4. 04BuildDomain swaps · mutagenesis · synthetic receptors

Tap a step to explore.

NextSee what this approach has produced↗