Science · listening at the cell surface
From ancient to future receptors.
We combine phylogenomics, synthetic biology, biochemistry, and plant biology to understand how plants perceive the environment.
One living dataset · one experimental loop
Evolution gives us the experiment.
The breadth of plant diversity, explored through phylogenomics, helps us decide where to look, what to test, and how to uncover new receptor functions.
1,750+plant species
50+plant orders
60M+proteins
Hundreds of thousandscell-surface receptors
Species in motion · a new selection on every visitGathering 30 species…
Our experimental loop
See. Test. Learn. Build. Repeat.
- 01SeePhylogenomics · sequence diversity · co-evolution
- 02TestReceptors · ligands · in planta data
- 03LearnStructure prediction · protein structure · biochemistry
- 04BuildDomain swaps · mutagenesis · synthetic receptors
- Repeat ↻